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5-Amino-1MQ
10mg|Freedom Diagnostics
$45.00
1
60-Day GuaranteeLab-TestedShips In 1 Day
Overview
NNMT Inhibition & Enzyme Selectivity
5-Amino-1MQ is a focus for researchers studying nicotinamide N-methyltransferase (NNMT), an enzyme implicated in cellular methylation balance and metabolic regulation. Research suggests it binds the substrate-binding site of NNMT with notable selectivity, leaving related SAM-dependent methyltransferases and NAD⁺ salvage enzymes largely unaffected. This selectivity makes it a useful tool for isolating NNMT-specific effects from broader methylation activity in cellular models.
Cellular Bioenergetics & Adipose Metabolism
In metabolic research, 5-Amino-1MQ is used to examine the relationship between NNMT activity and intracellular NAD⁺ availability. By suppressing the conversion of nicotinamide to 1-methylnicotinamide (1-MNA), studies investigate how restored NAD⁺ pools influence sirtuin signaling, mitochondrial function, and lipogenic gene expression within cultured adipocyte models and diet-induced obesity frameworks.
Skeletal Muscle & Regenerative Research
Recent studies have utilized 5-Amino-1MQ to investigate NNMT’s role in muscle tissue. Researchers examine how NNMT inhibition affects muscle satellite cell activity and age-associated shifts in regenerative capacity, using preclinical models to explore the enzyme’s involvement in cellular energy homeostasis and tissue maintenance.
Supplied as a stable, lyophilized reagent, it is intended strictly for laboratory research; it is not for human or veterinary administration.
For research use only.
Storage
To preserve research integrity, store unopened lyophilized vials:
- Store at -20°C for long-term preservation.
- Short-term storage at 2–8°C is acceptable before use.
- Protect from heat, moisture, and direct sunlight.
- Keep the vial tightly sealed until needed.
- Avoid repeated freeze-thaw cycles after reconstitution.
- Handle using standard laboratory procedures.
4 Stages Of Quality Control
01
Purity Verification
Every production batch undergoes analytical purity testing using validated laboratory methods to ensure consistency.
02
Identity Confirmation
Compound identity is confirmed through advanced analytical techniques prior to release.
03
Sterility & Handling
Each batch is produced under controlled laboratory conditions and handled according to strict quality procedures.
04
Certificate Review
Every lot is supported by an individual Certificate of Analysis (COA) documenting quality specifications and analytical results.
Certificate of Analysis
Every vial ships
with its own report
We don't publish brand-wide spec sheets and call them a “COA.” The certificate you receive references the actual lot number stamped on your vial, with the raw chromatograms attached.
- Lot-specific HPLC, MS, and LAL data
- Raw chromatogram + integration table
- Two-analyst sign-off with timestamps
- Permanent archive, searchable by lot ID
testimonials
loved by thousands
of customers
“Certificates matched the lot on every vial. That transparency is why I keep reordering.”
“Fast domestic shipping and the cold-chain packing arrived intact. Exactly as described.”
“The HPLC report was easy to cross-check by batch number. No guesswork at all.”
“Purity was consistent across three separate orders. Reproducibility I can trust.”
“Support answered a reconstitution question within hours — a real specialist, no bots.”
“Clear labeling and accurate dosing. Everything about the process felt professional.”
“Ordered Friday, testing Monday. The 1-business-day dispatch claim held up.”
“The on-chain COA record is a nice touch. Verifiable results, not just marketing.”
“Third-party lab data on every batch. This is how research supply should work.”
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