In Stock
5-Amino-1Mq
10mg
COA with every batch
Limited Quantity
NNMT Inhibition & Enzyme Selectivity
5-Amino-1MQ is a focus for researchers studying nicotinamide N-methyltransferase (NNMT), an enzyme implicated in cellular methylation balance and metabolic regulation. Research suggests it binds the substrate-binding site of NNMT with notable selectivity, leaving related SAM-dependent methyltransferases and NAD⁺ salvage enzymes largely unaffected. This selectivity makes it a useful tool for isolating NNMT-specific effects from broader methylation activity in cellular models.
Cellular Bioenergetics & Adipose Metabolism
In metabolic research, 5-Amino-1MQ is used to examine the relationship between NNMT activity and intracellular NAD⁺ availability. By suppressing the conversion of nicotinamide to 1-methylnicotinamide (1-MNA), studies investigate how restored NAD⁺ pools influence sirtuin signaling, mitochondrial function, and lipogenic gene expression within cultured adipocyte models and diet-induced obesity frameworks.
Skeletal Muscle & Regenerative Research
Recent studies have utilized 5-Amino-1MQ to investigate NNMT’s role in muscle tissue. Researchers examine how NNMT inhibition affects muscle satellite cell activity and age-associated shifts in regenerative capacity, using preclinical models to explore the enzyme’s involvement in cellular energy homeostasis and tissue maintenance.
Supplied as a stable, lyophilized reagent, it is intended strictly for laboratory research; it is not for human or veterinary administration.
For research use only.
5-Amino-1MQ is a synthetic small-molecule compound studied primarily as a selective inhibitor of the NNMT enzyme in metabolic research.
No. 5-Amino-1MQ is a small molecule rather than a peptide.
Researchers commonly investigate 5-Amino-1MQ in studies involving metabolism, NNMT inhibition, NAD+ biology, mitochondrial function, and adipose tissue.
Store refrigerated for short-term use or frozen for long-term preservation while protecting the vial from moisture and direct light.
5-Amino-1MQ is unique as a selective NNMT inhibitor, making it a valuable research compound for investigating cellular metabolism, NAD+ biology, mitochondrial function, and energy regulation in preclinical studies.
Overview
NNMT Inhibition & Enzyme Selectivity
5-Amino-1MQ is a focus for researchers studying nicotinamide N-methyltransferase (NNMT), an enzyme implicated in cellular methylation balance and metabolic regulation. Research suggests it binds the substrate-binding site of NNMT with notable selectivity, leaving related SAM-dependent methyltransferases and NAD⁺ salvage enzymes largely unaffected. This selectivity makes it a useful tool for isolating NNMT-specific effects from broader methylation activity in cellular models.
Cellular Bioenergetics & Adipose Metabolism
In metabolic research, 5-Amino-1MQ is used to examine the relationship between NNMT activity and intracellular NAD⁺ availability. By suppressing the conversion of nicotinamide to 1-methylnicotinamide (1-MNA), studies investigate how restored NAD⁺ pools influence sirtuin signaling, mitochondrial function, and lipogenic gene expression within cultured adipocyte models and diet-induced obesity frameworks.
Skeletal Muscle & Regenerative Research
Recent studies have utilized 5-Amino-1MQ to investigate NNMT’s role in muscle tissue. Researchers examine how NNMT inhibition affects muscle satellite cell activity and age-associated shifts in regenerative capacity, using preclinical models to explore the enzyme’s involvement in cellular energy homeostasis and tissue maintenance.
Supplied as a stable, lyophilized reagent, it is intended strictly for laboratory research; it is not for human or veterinary administration.
For research use only.
Storage
To preserve research integrity, store unopened lyophilized vials:
- Store at -20°C for long-term preservation.
- Short-term storage at 2–8°C is acceptable before use.
- Protect from heat, moisture, and direct sunlight.
- Keep the vial tightly sealed until needed.
- Avoid repeated freeze-thaw cycles after reconstitution.
- Handle using standard laboratory procedures.
4 Stages Of Quality Control
Purity Verification
Every production batch undergoes analytical purity testing using validated laboratory methods to ensure consistency.
Identity Confirmation
Compound identity is confirmed through advanced analytical techniques prior to release.
Sterility & Handling
Each batch is produced under controlled laboratory conditions and handled according to strict quality procedures.
Certificate Review
Every lot is supported by an individual Certificate of Analysis (COA) documenting quality specifications and analytical results.
Certificate of Analysis
Every vial ships
with its own report
We don't publish brand-wide spec sheets and call them a “COA.” The certificate you receive references the actual lot number stamped on your vial, with the raw chromatograms attached.
- Lot-specific HPLC, MS, and LAL data
- Raw chromatogram + integration table
- Two-analyst sign-off with timestamps
- Permanent archive, searchable by lot ID
Lot-specific COA on request
The signed certificate for the exact lot you receive ships with your order. Contact us to preview the current batch report.
Trusted by 150+ Customers
60-day money-back guaranteeon every order
