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LAB TESTED 99%+
MOTS-c 10mg vial

MOTS-c 10mg

All Tests Pass

Lab: Freedom Diagnostics

Latest Purity: 99.4%Latest Tested: Aug 13, 2026

In Stock

Best Seller

MOTS-c

10mg|Freedom Diagnostics

$59.00
1

COA with every batch

Limited Quantity

Dispatched within 24hrs99% PurityVerified batch COA

Mitochondrial-to-Nuclear Signaling

MOTS-c is a focus for researchers studying retrograde mitochondrial communication. As a peptide encoded within mitochondrial DNA, it is investigated for its ability to translocate to the nucleus under metabolic stress and influence nuclear gene expression. Studies use MOTS-c to examine how mitochondria signal to the nucleus to coordinate adaptive metabolic responses in cellular models.

AMPK Activation & Glucose Metabolism

In metabolic research, MOTS-c is investigated for its activation of the AMPK pathway, a central regulator of cellular energy balance. Researchers study how MOTS-c influences glucose uptake, insulin sensitivity, and substrate utilization in skeletal muscle and adipose models, examining its role in metabolic homeostasis under varying energy conditions.

Metabolic Stress & Exercise Models

Recent studies have utilized MOTS-c to investigate adaptive responses to metabolic stress. By examining its expression patterns during energy demand, researchers explore the peptide's role in cellular resilience, antioxidant gene regulation, and metabolic flexibility within preclinical frameworks.

Supplied as a purified, lyophilized powder, it is intended strictly for laboratory research; it is not for human or veterinary administration.

For research use only.

MOTS-c is a mitochondrial-derived peptide widely studied for its role in metabolic regulation, mitochondrial-to-nuclear signaling, and cellular energy homeostasis.

Yes. MOTS-c is a naturally occurring peptide encoded by mitochondrial DNA and is commonly investigated in preclinical research involving metabolism and cellular adaptation.

MOTS-c is commonly investigated in studies involving mitochondrial signaling, AMPK activation, glucose metabolism, insulin sensitivity, metabolic stress, exercise physiology, and cellular energy regulation.

MOTS-c should be stored in a cool, dry environment. For long-term stability, lyophilized vials are typically kept frozen and protected from heat, moisture, and direct sunlight.

MOTS-c is unique because it is encoded by mitochondrial DNA and can influence nuclear gene expression, making it a valuable research peptide for studying mitochondrial communication, metabolic adaptation, and cellular responses to energy stress.

Storage

To preserve research integrity, store unopened lyophilized vials:

  • Store at -20°C for long-term preservation.
  • Short-term storage at 2–8°C is acceptable before use.
  • Protect from heat, moisture, and direct sunlight.
  • Keep the vial tightly sealed until needed.
  • Avoid repeated freeze-thaw cycles after reconstitution.
  • Handle using standard laboratory procedures.
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